Publications by authors named "T J Roseboom"

The foundations of human wellbeing are laid in early life during the preconception stage and the 1,000-days of life from conception to the child's second birthday. This period is therefore receiving scrutiny as a concept for guiding pregnancy-care innovation and public health policy. The Dutch government took responsibility to invest in this.

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Objectives: Evidence suggests that high levels of air pollution and less green space increase depressive symptoms in adults. However, results are mixed and cross-cohort comparisons are scarce, largely due to heterogeneity in exposure assessment. Also, the impact of these exposures on the trajectory of depressive symptoms over time has been less studied.

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Article Synopsis
  • The study examines how exposure to famine during early pregnancy affects mortality rates in adults up to age 76, focusing on data from the 1944-1945 Dutch famine.
  • It found that women exposed to famine during early gestation had significantly higher overall mortality rates, as well as increased deaths from cancer and cardiovascular issues compared to those who were not exposed.
  • Interestingly, the same negative health effects were not observed in men, indicating a gender difference in the impact of prenatal famine exposure on long-term health outcomes.
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Prenatal adversity affects cognitive and brain aging. Both lipid and leptin concentrations may be involved. We investigated if prenatal undernutrition is associated with a specific blood lipid profile and/or leptin concentrations, and if these relate to cognitive function and brain aging.

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Objective: To evaluate reliability and validity of the Dutch version of the Infant Crying and Parent Well-Being (ICPW) tool in identifying parents struggling with infant crying in the first year of life.

Study Design: The original ICPW tool was translated into Dutch following established guidelines. The internal consistency and criterion validity of the Dutch ICPW tool were evaluated using a cross-sectional design.

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