Publications by authors named "T J Meretoja"
Article Synopsis
- The BREAST-Q tool assesses health-related quality of life (HRQL) for new breast cancer patients, but lacks previous reference data for this group.
- In a study of 627 newly diagnosed patients, 315 (50.2%) participated, where data on HRQL was collected and analyzed based on factors like age and body mass index (BMI).
- Results showed lower scores in physical well-being compared to norms, and highlighted that increased BMI and younger age correlated with lower psychosocial, sexual well-being, and breast satisfaction.
Background: The economic crisis that began in 2008 has severely affected Southern (Greece, Italy, Portugal, Spain) Western European (SWE) countries of Western Europe (WE) and may have affected ongoing efforts to eliminate viral hepatitis. This study was conducted to investigate the impact of the economic crisis on the burden of HBV and HCV disease.
Methods: Global Burden of Diseases 2019 data were used to analyse the rates of epidemiological metrics of HBV and HCV acute and chronic infections in SWE and WE.
Background: Combining cytotoxic chemotherapy or novel anticancer drugs with T-cell modulators holds great promise in treating advanced cancers. However, the response varies depending on the tumor immune microenvironment (TIME). Therefore, there is a clear need for pharmacologically tractable models of the TIME to dissect its influence on mono- and combination treatment response at the individual level.
View Article and Find Full Text PDFPurpose: Family history (FH) and pathogenic variants (PVs) are used for guiding risk surveillance in selected high-risk women but little is known about their impact for breast cancer screening on population level. In addition, polygenic risk scores (PRSs) have been shown to efficiently stratify breast cancer risk through combining information about common genetic factors into one measure.
Methods: In longitudinal real-life data, we evaluate PRS, FH, and PVs for stratified screening.
Purpose: The purpose of this study was to evaluate if it is possible to completely remove small breast cancer tumours with vacuum-assisted excision (VAE) under ultrasound guidance.
Methods: Women ≥ 50 years old with a biopsy proven invasive cancer ≤ 10 mm were selected between October 2021 and November 2021 based on referrals and enrolled in this prospective study. The patients underwent VAE within six weeks following biopsy to remove the tumour.