Duchenne muscular dystrophy (DMD) is a fatal X-linked disease characterised by severe muscle wasting. The mechanisms underlying the DMD pathology likely involve the interaction between inflammation, oxidative stress and impaired Ca signalling. Hypochlorous acid (HOCl) is a highly reactive oxidant produced endogenously via myeloperoxidase; an enzyme secreted by neutrophils that is significantly elevated in dystrophic muscle.
View Article and Find Full Text PDFA recent paper, entitled "" [1], investigated the impacts of climate change on Australian remote and regional Indigenous housing and it highlighted the significant reform necessary to maintain habitable conditions and improve energy resilience. The associated data is reported in this article. This dataset contains annual energy data and hourly internal temperature of six architectural models under current and future climates.
View Article and Find Full Text PDFThe appearance and integration of e-bikes in public space is a source of much debate worldwide. This paper offers insights to these debates by reflecting on how Deleuze and Guattari's concept of assemblage as territory helps us to understand the uptake of e-bike commuter cycling during the Covid-19 pandemic through empirical material from a study conducted in Sydney, Australia. Here we conceptualise commuter journeys in terms of processes of deterritorialisation and reterritorialisation; experienced through the affective territories generated by e-bikes.
View Article and Find Full Text PDF