Therapeutic potential of anti-ErbB3 chimeric antigen receptor natural killer cells against breast cancer.

ErbB3 is markedly overexpressed in breast cancer cells and is associated with resistance and metastasis. Additionally, ErbB3 expression levels are positively correlated with low densities of tumor-infiltrating lymphocytes, a marker of poor prognosis. Consequently, ErbB3 is a promising therapeutic target for cancer immunotherapy.

Clinical Manifestations.

Background: Neuropsychiatric symptoms (NPS) are highly prevalent in older adults. While the association between NPS and cognitive decline in older adults is widely acknowledged, there remains a lack of specificity regarding emerging NPS and cognitive outcomes in cognitively unimpaired older individuals. Our study assessed the incidence of NPS development, its link to cognitive decline, and other factors associated with development of MCI among cognitively unimpaired older adults without NPS at baseline.

First report of iron-overload myopathy due to secondary hemochromatosis in a dog.

Importance: Hemochromatosis is rare in domestic animals, and iron-induced myopathy has not been reported in veterinary medicine. This case is the first report of iron-overload myopathy owing to hemochromatosis in a dog.

Case Presentation: A 9-year-old spayed female Donggyeong dog presented with severe forelimb lameness.

1.6-Inch Transparent Micro-Display with Pixel Circuit Integrated microLED Chip Array by Misalignment-Free Transfer.

Recent advances in mass transfer technology are expected to bring next-generation micro light-emitting diodes (µLED) displays into reality, although reliable integration of the active-matrix backplane with the transferred µLEDs remains as a challenge. Here, the µLED display technology is innovated by demonstrating pixel circuit-integrated micro-LEDs (PIMLEDs) and integrating them onto a transparent glass substrate. The PIMLED comprises of low-temperature poly-silicon transistors and GaN µLED.

Exfoliation of triazole-based CN, CN, and CN nanosheets for efficient photocatalytic ammonia production.

Atomically thin two-dimensional nanosheets of nitrogen-rich CN, CN, and CN are synthesized by sonochemical process. Despite their high nitrogen content, their triazole-based crystal structures remain intact after exfoliation. Among the present materials, the nitrogen-richest CN nanosheets display the highest photocatalytic activity for ammonia production, highlighting the synergetic effect of composition control and exfoliation.