Diet-wide analyses for risk of colorectal cancer: prospective study of 12,251 incident cases among 542,778 women in the UK.

Uncertainty remains regarding the role of diet in colorectal cancer development. We examined associations of 97 dietary factors with colorectal cancer risk in 542,778 Million Women Study participants (12,251 incident cases over 16.6 years), and conducted a targeted genetic analysis in the ColoRectal Transdisciplinary Study, Colon Cancer Family Registry, and Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO).

Defluorination of various perfluoro alkyl acids and selected PFOA and PFOS monomers by Acidimicrobium sp. Strain A6 enrichment cultures.

Per- and polyfluoroalkyl substances (PFAS) have emerged as a diverse class of environmental pollutants, garnering increasing attention due to their various structural types and potential ecological impacts. The impact of select PFAS on environmental microorganisms and the potential for microbial degradation of certain PFAS are timely research topics. In this study, we conducted a series of batch incubation to investigate the effects of C-C perfluoroalkyl carboxylic acids (PFCAs) and perfluorosulfonic acids (PFSAs), as well as linear and branched perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) monomers, on the Feammox reaction and Acidimicrobium sp.

Associations of body composition measures with circulating insulin-like growth factor-I, testosterone, and sex hormone-binding globulin concentrations in 16,000 men.

Background: Adiposity is positively associated with risk of some cancer sites and other health conditions in men; however, it is unclear if endogenous hormones play a role in these associations. We examined how body composition, measured from magnetic resonance imaging (MRI) and common measures of adiposity (e.g.