Publications by authors named "T J Hathaway"
mGluR2 receptors are widely expressed in limbic brain regions associated with memory, including the hippocampal formation, retrosplenial and frontal cortices, as well as subcortical regions including the mammillary bodies. mGluR2/3 agonists have been proposed as potential therapeutics for neurological and psychiatric disorders, however, there is still little known about the role of these receptors in cognitive processes, including memory consolidation. To address this, we assessed the effect of the mGluR2/3 agonist, eglumetad, on spatial memory consolidation in both mice and rats.
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- Coastal acidification in the southeastern U.S. is driven by biological processes, land runoff, and rising atmospheric CO2, leading to harmful effects on marine life, particularly in shellfish, finfish, and corals.
- Research indicates that acidification particularly affects larval stages of species, increases pesticide toxicity, and hinders vital functions like calcification and reproduction in corals.
- The Southeast Coastal and Ocean Acidification Network (SOCAN) aims to address these challenges through research, monitoring, and collaboration among scientists, resource managers, and governments to mitigate the impacts of acidification.
PPCA has historically been considered detrimental to donor quality in LT, but transplantation of grafts from this group of donors is now routine. Our study aims to evaluate the outcomes associated with use of donors with a history of PPCA in the pediatric population. This study is a single-center retrospective analysis of all pediatric LTs performed over an 18-year period.
View Article and Find Full Text PDFProgestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology.
Cochrane Database Syst Rev
November 2019
Article Synopsis
- Progesterone is important for preparing the uterine lining for pregnancy, and low levels may contribute to miscarriages; thus, progestogens are used to help prevent these early losses.
- Recent updates in research have raised concerns about a specific study, prompting its removal from included studies until further investigation is completed.
- The review aims to evaluate the effectiveness and safety of progestogens in preventing recurrent miscarriages through an analysis of several relevant clinical trials.
Article Synopsis
- Postoperative atrial fibrillation/flutter (POAF) is the most common arrhythmia following liver transplantation, occurring in about 10% of patients within the first few days after surgery.
- The strongest risk factors for developing POAF include a pre-existing history of atrial fibrillation and coronary artery disease, with abnormal cardiac stress tests also indicating higher risk.
- Patients with POAF experience longer hospital stays and increased mortality rates, highlighting its significance as a marker for poorer clinical outcomes after liver transplantation.