Publications by authors named "T J Carroll"
Background And Purpose: In acute ischemic stroke, the amount of "local" CBF distal to the occlusion, i.e. all blood flow within a region whether supplied antegrade or delayed and dispersed through the collateral network, may contain valuable information regarding infarct growth rate and treatment response.
View Article and Find Full Text PDFArticle Synopsis
- Neurodegenerative diseases like Alzheimer's are linked to problems with mitochondria, specifically mitophagy, which is the process of removing damaged mitochondria.
- Research indicates that mutated tau proteins can inhibit this process, affecting cell health during oxidative stress.
- In this study, it was found that certain tau mutations reduce levels of a key mitophagy receptor, FKBP8, which could help explain tau's role in mitochondrial dysfunction related to Alzheimer's and suggest FKBP8 as a target for future treatments.
Recent federal initiatives demonstrate that improving adult outcomes for youth with disabilities is a high priority for the United States. The U.S.
View Article and Find Full Text PDFEpithelial tubule interconnection driven by HGF-Met signaling in the kidney.
Proc Natl Acad Sci U S A
December 2024
The formation of functional epithelial tubules is critical for the development and maintenance of many organ systems. While the mechanisms of tubule formation by epithelial cells are well studied, the process of tubule anastomosis-where tubules connect to form a continuous network-remains poorly understood. In this study, we utilized single-cell RNA sequencing to analyze embryonic mouse kidney tubules undergoing anastomosis.
View Article and Find Full Text PDFImpact of Social Deprivation on Cubital Tunnel Syndrome Treatment Timeline.
J Hand Surg Glob Online
November 2024
Purpose: The purpose of this study was to establish the impact of area deprivation index (ADI) on treatment timelines of patients with cubital tunnel syndrome (CuTS). We hypothesize that increased social deprivation will correlate with increased time between care milestones from presentation to surgery.
Methods: This is a retrospective study of patients diagnosed with CuTS who underwent surgical intervention at a single academic institution.