Publications by authors named "T J Carlisle"
Article Synopsis
- The study investigates the link between plasma glial fibrillary acidic protein (GFAP) and amyloid levels in relation to cognitive outcomes, focusing on the fornix structure in individuals with Alzheimer's disease (AD).
- Researchers assessed plasma GFAP and amyloid-β42 levels in a cohort of 99 older adults and used advanced imaging techniques to evaluate the fornix, a brain structure important for memory.
- Results showed that higher plasma GFAP levels correlated with microstructural changes in the fornix, which in turn mediated the relationship between GFAP and verbal memory performance, particularly in individuals with low amyloid levels.
Introduction: Cognitive decline is common in Parkinson's disease (PD). Calculating personalized risk of cognitive decline in PD would allow for appropriate counseling, early intervention with available treatments, and inclusion in disease-modifying trials.
Methods: Data were from the Parkinson's Progression Markers Initiative cohort.
Background: Longitudinal assessment of functional abilities in Parkinson's disease (PD) is needed to determine the efficacy of cognitive interventions in providing meaningful improvements in daily life. Additionally, subtle changes in instrumental activities of daily living may precede a clinical diagnosis of dementia and could aid earlier detection of and intervention for cognitive decline.
Objective: The primary goal was to validate the longitudinal application of the University of California San Diego Performance-Based Skills Assessment (UPSA).
Angus and Red Angus-based yearling heifers (n = 40) and lactating cows (n = 51) were each used in a complete randomized design and stratified by weight and body condition score to one of two treatments: (1) pressed supplement block containing rumen undegradable protein (RUP) and (2) pressed supplement block containing rumen degradable protein (RDP). Heifer and cow supplement intake displayed (p < 0.01) a treatment × period interaction.
View Article and Find Full Text PDFObjectives: Abuse of opiates, cocaine, and lipophilic inhalants (e.g., toluene) can damage brain myelin and cause acute toxic leukoencephalopathy (TL), but little is known about recovery or prognosis in this condition.
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