Publications by authors named "T Iyobe"

Background: We aimed to determine whether elevated preoperative serum inflammatory markers influence surgical site infections (SSIs) and periprosthetic joint infections (PJIs) after primary total hip arthroplasty (THA).

Methods: In this retrospective single-institution study, 1115 patients who underwent primary THA were enrolled. Cases of SSI/PJI were identified.

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  • Greater trochanteric fractures can occur during total hip arthroplasty (THA) when using the anterolateral approach, and this study aimed to explore how bone mineral density (BMD) and the shape of the femur affect the risk of these fractures.
  • A total of 209 hips were analyzed after THA, with a focus on identifying fractures and assessing the correlation between bone density and femoral morphology through multivariate analysis.
  • Results indicated that a bone density below 80% of the young adult mean (YAM) combined with a specific femoral shape (Type B) significantly increased the risk of greater trochanteric fractures during surgery.
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  • - The study investigates how male mice switch from one defensive behavior to another, specifically from freezing to flight, during fear conditioning experiments.
  • - Results show that flight behaviors are influenced by the context of the threat, the intensity of stimuli, the conditioning schedule, and the subject's state, with salient auditory stimuli being key triggers.
  • - The findings suggest that flight behavior is a complex response, incorporating various learned and innate factors, rather than just a straightforward conditioned or fear response.
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Adipose-derived stem cells (ADSCs) have been studied for many years as a therapeutic option for osteoarthritis (OA); however, their efficacy remains insufficient. Since platelet-rich plasma (PRP) induces chondrogenic differentiation in ADSCs and the formation of a sheet structure by ascorbic acid can increase the number of viable cells, we hypothesized that the injection of chondrogenic cell sheets combined with the effects of PRP and ascorbic acid may hinder the progression of OA. The effects of induction of differentiation by PRP and formation of sheet structure by ascorbic acid on changes in chondrocyte markers (collagen II, aggrecan, Sox9) in ADSCs were evaluated.

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