[Treatment of asthenic disorders in patients with psychoautonomic syndrome: results of a multicenter study on efficacy and safety of ladasten].

The study was carried out in 28 clinical centers of Russia. The data on 728 patients with psychoautonomic syndrome (91.6% of the total sample) were available for statistical analysis.

[Treatment of chronic back pain with antidepressant cymbalta: an experimental study].

Thirty-two patients at the acute stage of chronic back pain have been studied. Cymbalta was used as a monotherapy in dosage 60 mg daily during 6 weeks simultaneously with traditional non-pharmacological therapy. Treatment efficacy was assessed using self-rating methods and quantitative scales measuring pain intensity as well as Spilberger trait/state anxiety inventory, Beck depression scale, Plutchik scale measuring psychological defense mechanisms, quality of sleep, quality of life and evaluation of autonomic dysfunction.

[Anxiety-depressive disorders in patients with type 2 diabetes mellitus complicated with acute coronary syndrome].

Psychological status of 140 patients with type 2 diabetes mellitus (DM) and acute coronary syndrome (ACS) was studied on the 12-th day after the moment of admission to the cardioreanimation department and in 6 months after discharge from hospital. Spielberger questionnaire was used for assessment of level of personal and reactive anxiety, Beck scale -- for estimation of level of depression, and Holmes - Ray scale -- for calculation of total number of stressful events. Average level of anxiety in acute period of ACS corresponded to high level of anxiety disorders (reactive anxiety score 47.