Publications by authors named "T Itagaki"

The global prevalence of oral squamous cell carcinoma (OSCC) has been increasing. OSCC at the advanced stage tends to resist conventional treatment and causes local recurrence and distant metastasis, resulting in poor prognosis. Therefore, detecting this cancer at an early stage and performing early intervention are important.

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The ribonuclease T1 family, including RNase Po1 secreted by , exhibits antitumor activity. Here, we resolved the Po1/guanosine-3'-monophosphate complex (3'GMP) structure at 1.75 Å.

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Article Synopsis
  • A study in Yamagata, Japan, analyzed blood samples from different years (1976-2019) to understand the prevalence of enterovirus D68 (EV-D68), a virus that was uncommon in the 20th century.
  • The research found that neutralizing antibody positive rates in people under 20 years increased significantly over the years, suggesting rising exposure to EV-D68.
  • The study also indicated that while children show a gradual increase in seroprevalence, adults reach a high plateau, indicating consistent transmission of the virus among children even when it was rarely detected.
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