Publications by authors named "T Isosu"

Background: The use of pressure-controlled ventilation (PCV) for anesthesia management is becoming more commonly used. Chest drainage is commonly performed after thoracic surgery, and the negative pressure it generates might affect the transpulmonary pressure (TPP). In the present study, we investigated how chest drainage could affect ventilating conditions during PCV.

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Article Synopsis
  • The case presented involves a 70-year-old man undergoing lower lobectomy with pressure-controlled ventilation (PCV) during one lung ventilation (OLV) to avoid high airway pressure.
  • After placing a chest drainage tube, there was a dramatic drop in tidal volume (TV) from 450 ml to 250 ml, prompting a switch to volume-controlled ventilation to maintain the target TV.
  • The subsequent re-thoracotomy revealed no significant issues, suggesting that the decrease in TV could be attributed to increased negative pressure in the chest cavity affecting lung volume post-surgery.
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Background: The SedLine sensor processes (Masimo Corporation; Irvine, CA, USA) raw electroencephalogram (EEG) signals and displays the depth of sedation as a Patient State Index (PSi). Reliance on standard processed EEG data and failure to recognize age-related effects can lead to an erroneous interpretation that low-amplitude EEG findings in an older patient signify an insufficient depth of anesthesia presented as abnormally high PSi values (AHPSi). We hypothesized that the incidence of AHPSi would decrease with the use of the recently-updated version of the SedLine sensor, in which the Bispectral Index (BIS) values were used to titrate anesthesia.

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