Publications by authors named "T Ingvarsson"
Purpose: To identify potential prognostic factors for patient-reported outcomes in an Icelandic cohort of ACL injured subjects.
Methods: All knee MRI reports written in Iceland between the years 2001 to 2011 were read to identify individuals with a possible ACL injury. These individuals were contacted and asked to complete an online questionnaire regarding their injury and current knee related health.
Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 11 osteoarthritis phenotypes, 52 of which have not been associated with the disease before. We report thumb and spine osteoarthritis risk variants and identify differences in genetic effects between weight-bearing and non-weight-bearing joints.
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- Most prosthetic limbs can move autonomously but are often not recognized by users as part of their body.
- Current technology limits the connection and communication between robotic limbs and the user, hindering performance.
- The article suggests that using osseointegration, improved neural signal amplification, and sensory feedback can enhance bionic limbs, promoting their clinical adoption with proper redesign and rehabilitation.
The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland.
Arthritis Rheumatol
November 2021
Objective: Biomarkers for diagnosis and progression of osteoarthritis (OA) are lacking. This study was undertaken to identify circulating biomarkers for OA that could predict disease occurrence and/or progression to joint replacement.
Methods: Using the SomaScan platform, we measured 4,792 proteins in plasma from 37,278 individuals, of whom 12,178 individuals had OA and 2,524 had undergone joint replacement.