Publications by authors named "T Inatomi"

Article Synopsis
  • The study aimed to enhance the accuracy of predicting glaucomatous visual field (VF) impairment by using pointwise total deviation (TD) values with a machine-learning method called random forest model (RFM) and examining the role of ganglion cell-inner plexiform layer (GCIPL) thickness.
  • Researchers analyzed data from 89 eyes with open-angle glaucoma that had cataract surgery, using various predictive models to calculate mean TD.
  • Results showed that RFM provided more accurate predictions than traditional methods, and incorporating GCIPL measurements did not significantly improve the model’s accuracy.
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Article Synopsis
  • A study evaluated the effectiveness and safety of cultured human corneal endothelial cells (cHCEC) for treating bullous keratopathy (BK) across phase II and III clinical trials involving 27 patients.
  • The primary goal was to achieve a corneal endothelial cell density of at least 1000 cells/mm by 24 weeks post-transplant, which was successful in 94.1% of cases, alongside significant reductions in corneal thickness and improvements in vision.
  • While 88.9% of patients experienced mild and temporary adverse events, the cHCEC treatment showed promising results in restoring corneal function and visual acuity.
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Purpose: To investigate the visual prognosis of ocular surface squamous neoplasia (OSSN) after tumor resection and ocular surface reconstruction, and clarify factors that influence recurrence.

Study Design: Retrospective cohort study.

Methods: Medical records of all patients who underwent surgical treatment for OSSN at our hospital between January 1996 and December 2019 were reviewed.

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Article Synopsis
  • The study aimed to evaluate the long-term outcomes of cultivated oral mucosal epithelial transplantation (COMET) combined with limbal-rigid contact lens therapy in patients with severe ocular surface disease (OSD).
  • Researchers reviewed data from 18 patients over a period from 2002 to 2019, focusing on factors like best-corrected visual acuity (BCVA) and Ocular Surface Grading Scores (OSGS) before and after treatment.
  • Results showed a significant improvement in vision and ocular surface conditions with no major complications, confirming the effectiveness of this combined treatment for improving quality of life in these patients.
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Purpose: To identify primary cilia in human corneal endothelial cells (CECs) obtained from patients with bullous keratopathy (BK).

Methods: This study involved CEC specimens obtained from 10 eyes of 10 consecutive patients (three males and seven females; mean age: 74.5 years, range: 68-90 years) with BK who underwent Descemet's stripping automated endothelial keratoplasty at Baptist Eye Institute, Kyoto, Japan between August 2019 and September 2020.

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