Publications by authors named "T Inagami"
Article Synopsis
- The Concise Guide to PHARMACOLOGY 2023/24 offers a summarized overview of approximately 1800 drug targets and around 6000 interactions with 3900 ligands, mostly in a tabular format.
- It focuses on selective pharmacology and includes links to an open access knowledgebase for more detailed drug information.
- The guide divides drug targets into six major categories, providing essential summaries and guidance based on the latest pharmacological data available as of mid-2023, while serving as an official resource by the International Union of Basic and Clinical Pharmacology.
Article Synopsis
- The Concise Guide to Pharmacology 2021/22 offers a streamlined overview of nearly 1900 human drug targets, focusing on selective pharmacology and organized mainly in tables for quick reference.
- The guide serves as a reliable, citable resource that distills extensive online content while ensuring it reflects the status as of mid-2021, distinct from ongoing database updates.
- Key pharmacological targets include G protein-coupled receptors, ion channels, and enzymes, with official nomenclature and references provided to assist further research and understanding.
Chronic wounds are among the most devastating and difficult to treat consequences of diabetes. Dysregulation of the skin renin-angiotensin system is implicated in abnormal wound healing in diabetic and older adults. Given this, we sought to determine the effects of topical reformulations of the angiotensin type 1 receptor blockers losartan and valsartan and the angiotensin-converting enzyme inhibitor captopril on wound healing in diabetic and aged mice with further validation in older diabetic pigs.
View Article and Find Full Text PDFWounds are among the most common, painful, debilitating and costly conditions in older adults. Disruption of the angiotensin type 1 receptors (AT1R), has been associated with impaired wound healing, suggesting a critical role for AT1R in this repair process. Biological functions of angiotensin type 2 receptors (AT2R) are less studied.
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