Publications by authors named "T Imanishi"

Schizophyllum commune, a common wood-decay mushroom known for its extremely high genetic variation and as a rare cause of human respiratory diseases, could be a promising model fungus contributing to both biology and medicine. To better understand its phenotypic variation, we developed an image analysis system that quantifies morphological and physiological traits of mycelial colonies in Petri dishes. This study evaluated growth of six wild and one clinical isolates of Japanese S.

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  • Recent advances in neonatal care have improved survival rates for extremely low-birth-weight infants (ELBWIs), but not the quality of survival without complications.
  • This study used time-domain near-infrared spectroscopy (TD-NIRS) to monitor deep brain activity in ELBWIs, showing that optical signals were detectable through their heads.
  • Findings revealed that total hemoglobin concentration and tissue oxygen saturation decreased in the first month after birth, suggesting that TD-NIRS could aid in managing the cerebral health of ELBWIs in intensive care.
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  • - Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and early detection is difficult, prompting the development of a novel detection method called Comprehensive Serum Glycopeptide Spectral Analysis (CSGSA).
  • - CSGSA identifies early-stage EOC by examining changes in glycan structures in serum glycoproteins alongside traditional tumor markers, achieving high accuracy (AUC of 0.924) in distinguishing early-stage EOC from controls.
  • - This method significantly outperforms existing tumor markers, like CA125 and HE4, especially in differentiating early-stage ovarian clear cell carcinoma from endometrioma, showcasing strong potential for enhanced early detection of EOC.
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Background: Some Japanese patients with cancer pain have negative beliefs regarding opioid therapy. The Japanese version of the Barriers Questionnaire II (JBQ-II) determines barriers to cancer pain management. Few studies reported JBQ-II scores in Japan, and none focused on pharmacists.

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Currently, hepatitis B virus (HBV) core antibody (anti-HBc antibody) and HBV core-related antigen (HBcrAg) are widely used as serum markers for diagnosis based on the HBV core region. This review focused on anti-HBc antibodies and HBcrAg and aimed to summarize the clinical significance of currently used assay systems and the issues involved. While anti-HBc is very significant for clinical diagnosis, the clinical significance of quantitative assay of anti-HBc antibody has been reevaluated with improvements in diagnostic performance, including its association with clinical stage and prediction of carcinogenesis and reactivation.

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