Publications by authors named "T Iinuma"
Article Synopsis
- Age-related changes in macrophage polarization in the trigeminal ganglion (TG) contribute to increased sensitivity to intra-oral pain after mucosal incisions, particularly in older SAMP8 mice compared to younger SAMR1 mice.
- The study involved measuring pain thresholds and analyzing the presence of specific inflammatory macrophage types (M1 and M2) in the TG over a period of 21 days post-injury.
- Results showed that enhanced CCL2 signaling from M1-macrophages in older mice led to greater pain hypersensitivity, indicating a link between aging, macrophage activity, and prolonged pain response.
Article Synopsis
- A study examined the link between malnutrition and oral health in older adults (aged 85+) using the GLIM criteria for diagnosing malnutrition, involving 519 participants from Tokyo.
- Findings revealed that 17.1% of participants were malnourished and had significant issues in oral health such as decreased maximum occlusal force, meal enjoyment, and various specific oral health problems.
- Cox regression analysis indicated specific oral health declines and problems (like difficulty in eating and maintaining teeth) were strongly associated with increased malnutrition risk among the elderly.
Article Synopsis
- - The traditional healthcare approach often overlooks patients' personal experiences and strengths, focusing mainly on disease treatment. Person-centered care aims to align medical decisions with individual values and preferences, particularly for those with chronic conditions.
- - This paper seeks to enhance care for rhinitis and asthma by developing digital care pathways and incorporating real-world evidence to create a more patient-centered approach.
- - Key components of the review include advancements in mHealth, the integration of artificial intelligence, a novel classification system for airway diseases, and proposals for the ARIA 2024 guidelines, all targeting a sustainable and applicable healthcare model.
Purpose: This systematic review examined the effectiveness of soft denture relining (SDR) materials.
Study Selection: A comprehensive search of MEDLINE, Cochrane Library, and ICHUSHI was conducted up to July 26, 2020. Target outcomes were patient satisfaction, oral health-related quality of life (OHRQOL), masticatory ability (MA), denture functional duration, residual ridge resorption (RRR), and microbial contamination.
Objectives: IgG4-related disease (IgG4-RD) is a systemic autoimmune disease with an unknown etiology, affecting single/multiple organ(s). Pathological findings include the infiltration of IgG4-producing plasma cells, obliterative phlebitis, and storiform fibrosis. Although immunological studies have shed light on the dysregulation of lymphocytes in IgG4-RD pathogenesis, the role of non-immune cells remains unclear.
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