Publications by authors named "T Iino"
Background/aim: Cryoablation is a new, minimally invasive option for local tumor therapy that is attracting attention due to its potential interactions with the immune system. The purpose of this study was to evaluate the efficacy of cryoablation for local control of bone and soft tissue lesions, to elucidate risk factors for recurrence, and to clarify histological changes.
Patients And Methods: Participants comprised 25 patients who underwent cryoablation for 53 discrete lesions of bone or soft tissue recurrence after resection or as metastases of cancer or sarcoma.
A novel bacterium, designated as strain LOR1-02 and isolated from a lichen sample collected from Kham Riang Subdistrict, Kantharawichai District, Maha Sarakham Province, Thailand, underwent thorough investigation utilizing a polyphasic taxonomic approach. Strain LOR1-02 demonstrated growth within a temperature range of 20-42 °C (optimal at 30 °C), pH range of 5.0-7.
View Article and Find Full Text PDFThe pathophysiology of variant transthyretin (TTR) amyloidosis (ATTRv) is associated with destabilizing mutations in the TTR tetramer. However, why TTR with a wild-type genetic sequence misfolds and aggregates in wild-type transthyretin amyloidosis (ATTRwt) is unknown. Here, we evaluate kinetic TTR stability with a newly developed ELISA system in combination with urea-induced protein denaturation.
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- Strain MIZ03 is a new species of neutrophilic iron-oxidizing and -reducing bacterium isolated from a wetland in Japan, characterized as motile and Gram-stain-negative.
- This strain can grow through both chemolithoautotrophic and chemoorganotrophic processes, utilizing aerobic respiration and fermentation.
- Phylogenetic analyses reveal a close relationship to another bacterium, with 98.5% similarity in the 16S rRNA gene, leading to the proposal of a new species name for strain MIZ03.
Thrombopoietin receptor agonist (TPO-RA) is effective for aplastic anemia (AA) and idiopathic thrombocytopenic purpura (ITP). However, the risk of thrombosis during ITP treatment with TPO-RA is higher than without TPO-RA. It is unclear whether TPO-RA increases the risk of thrombosis in patients with AA.
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