Publications by authors named "T Ichihashi"
Article Synopsis
- - A study on 367 patients undergoing ablation for paroxysmal atrial fibrillation (AF) compared outcomes between radiofrequency ablation (RFA) and cryoablation (CRA) to see how inducibility affects AF recurrence, following patients for 600 days.
- - Results showed no significant difference in AF recurrence rates between the RFA (17%) and CRA (19%) groups, but inducibility through burst pacing (BP) was a strong predictor of recurrence in the RFA group, especially with low-frequency burst pacing (LFBP).
- - In contrast, inducibility by BP after CRA did not predict recurrence, indicating that different ablation methods might yield different risks for returning AF.
Article Synopsis
- The study investigates protein-rich inclusions in neurodegeneration, noting that current iPSC models lack reproducibility and speed in developing these inclusions.
- Researchers created new iPSC models that allow for rapid production of CNS cells with proteins prone to aggregation, enabling the tracking of inclusions at a single level.
- They identified various inclusion types with differing effects on neuron survival and isolated proteins that could influence toxicity, paving the way for improved drug development for neurodegenerative diseases.
Hemodialysis (HD)-induced myocardial stunning, characterized by transient left ventricular systolic dysfunction during HD, has been reported to be common and associated with a poor prognosis. However, the pathophysiology is not fully understood. We herein report a case of HD-induced myocardial stunning without obstructive coronary artery disease complicated by coronary microvascular dysfunction (CMD), suggesting that CMD plays a crucial role in the pathophysiology of this disease.
View Article and Find Full Text PDFObjective: To comprehensively evaluate diagnostic algorithms for myocardial infarction using a high-sensitivity cardiac troponin I (hs-cTnI) assay.
Patients And Methods: We prospectively enrolled patients with suspected myocardial infarction without ST-segment elevation from nine emergency departments in Japan. The diagnostic algorithms evaluated: (i) based on hs-cTnI alone, such as the European Society of Cardiology (ESC) 0/1-h or 0/2-h and High-STEACS pathways; or (ii) used medical history and physical findings, such as the ADAPT, EDACS, HEART, and GRACE pathways.
Article Synopsis
- - This study investigates how deep brain stimulation (DBS) affects gait performance in patients with advanced Parkinson's Disease, particularly focusing on the effects of directional current steering.
- - Eleven patients who had DBS implants performed walking tests to analyze their gait with varying stimulation angles, but the results showed no significant changes in most parameters during the tests except for stride length.
- - The findings suggest that using directional steering for stimulation could enhance gait in Parkinson's patients without triggering unwanted side effects, particularly those linked to the pyramidal tract.