[Allokin-alpha - new approaches in the treatment of chronic virus Epstein-Barr infections.].

Introduction: Epstein-Barr virus causes recurrent infectious mononucleosis-like symptoms. Today it is shown that the poisons of insects and animals are rich sources of antimicrobial substances (peptides) and contain a wide range of active biological compounds. Antimicrobial peptides play an important role in the immune response of the innate immunity of the host in the presence of pathogenic microorganisms.

[Spatial structure of natural foci of hantavirus on the territory of Northwestern Caucasus].

For the period from 2001 to 2011 zoological and epizootological studies in more than 100 points of Northwestern Caucasus including territories of Krasnodar Region and Republic of Adygea were carried out. 8723 specimens of small mammals represented by 20 rodent species and 7 insectivorous species were captured and examined. Organs and blood from 5057 specimens of creatures were studied for hantavirus infection.

[Role of intrarenal product TNF-alpha in the development of glomerular and tubulointerstitial tissues changes in elderly patients with diabetic nephropathy].

The aim of this study was to investigate the expression of TNF-alpha produced in the kidney in patients with diabetic nephropathy (DN) type 2 diabetes and its impact on the development of glomerular and tubulointerstitial tissue changes in these patients. The survey was conducted in 49 elderly patients (mean age 66.53 +/- 3.

[The concentration of homocysteine in blood serum among indigene and outsider population of priamurye].

The study evaluated the concentration of homocysteine in the most numerous groups of indigene population of Priamurye (Even, Ultch, Nanai) as compared with adjacent to them outsider population. The technique of random sampling was applied to select 82 Even, 89 Ultch, 95 Nanai and for comparing the representatives of outsider male and female population in statistically comparable numbers. The concentration of homocysteine was determined with luminescence immunoassay using the analyzer immulite 1000 (Diagnostic Products Corporation, USA) and applying Siemens kits (USA).

[Influence of immunoglobulins on clinical laboratory picture and morphological changes in patients with mesangial-proliferative glomerulonephritis: age aspects].

The article presents data of 77 mesangial proliferative glomerulonephritis (MezPGN) patients, aged 20 to 71 years. The effect of deposits of immunoglobulins in the kidney tissue to the index of blood pressure and laboratory parameters of disease activity in MezPGN patients regardless of age is shown. The data demonstrate that the presence of IgM deposits in kidney tissue is unfavorable prognostic sign of MezPGN flow.