Publications by authors named "T I Zavadskaia"

Rearrangement of the locomotor generator activity evoked by phasic electrical stimulation of different descending systems has been investigated on decerebrated immobilized cats. The rearrangement heavily depends on the stimulation phase. A maximal increase of the locomotor cycle duration by electrical stimulation of the Deiters nucleus takes place in the end of an "extensor" phase.

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Data on reorganization of the efferent activity parameters of the forelimb locomotor generators during electrical stimulation of the descending systems were obtained during experiments on immobilized decerebrate cats. It has been found that a generator controlling the forelimb locomotor movement is characterized by existence of such a stable state when total influence of different descending systems on this generator is extremely limited. A conclusion is made that the sense of the activity reorganization in the locomotor generator of a forelimb under the effect of signals from descending systems brings the motor program to such a dynamic relation with a supraspinal inflow which provides sufficiently limitation and balancing of the influences of corresponding descending systems on the interneuronal nets, determining time and phase characteristics of the activity of these generators.

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Rearrangement of the scratching generator activity evoked by phasic electrical stimulation of different descending systems has been investigated on decerebrated immobilized cats. This rearrangement heavily depends on the stimulation phase. Maximal increase of the scratching cycle duration by electrical stimulation of Deiters' nucleus, red nucleus and pyramidal tract takes place in the first half of an aiming phase.

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The comparative assessment of the clinico-economical efficiency of the conservative and surgical treatment of the patients with duodenal ulcer disease was carried out. Direct expenses for surgical treatment were 2.5-fold higher than those for conservative treatment.

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It is shown that the state of the segmental apparatus of the lumbal spinal cord of immobilized intercollicularly decerebrated cats during formation of a scratching generator is essentially different from that of a spinal animal. The excitability of "aiming" and "scratching" motoneurons increases, recurrent and reciprocal Ia inhibition of motoneurons becomes stronger and influence of Ib afferents weaker. The flexor reflex afferents exert inhibitory influences on "aiming" motoneurons.

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