[Cytogenetic effects of alpha-irradiation due to incorporated 239Pu].

Intravenous injection of plutonium dioxide with 1-2 microns particle sizes in amount of 92.5, 46.3 and 23.

[The frequency of chromosome aberrations in rat bone marrow cells in the late period after a single uptake of tritium].

A prolonged self-maintenance of haemopoietic tissue cells with stable chromosome rearrangements following a single intake of tritium oxide in the amount of 24 MBq/g of body weight (absorbed dose of 11 Gy) is shown. Mutant cells revealed long after the radionuclide exposure are descendants of stem-cell precursors, bearing stable chromosome aberrations during the period of formation of radiation injury after the radionuclide administration.

[Frequency of structural chromosome aberrations in the hepatocytes of rats exposed to polymeric 239Pu].

Intravenous injection of polymeric 239Pu(IV) nitrate (166.5, 55.5 and 18.

[Structural chromosomal damages in myelokaryocytes exposed to plutonium-239 dioxide].

Plutonium 239 dioxide, with particle sizes of 1-2 micron, injected to Wistar rats intravenously in doses of 92.5, 46.3, and 23.

[Frequency of chromosome aberration in liver cells of rats of various ages].

Frequency of chromosome aberrations in the liver cells of hepatectomized Wistar rats aged 3, 9, 12 and 18 months was studied. Changes in the number of chromosomes and damage of their structure at the metaphase stage of the first division hepatocytes are analyzed. The content of aneuploid cells was 1-3% of the total number of metaphases studied and did not change with the age of animals.