Publications by authors named "T I Umeizudike"
Article Synopsis
- The DCA study investigates how dietary factors influence chronic kidney disease progression and nephropathy, emphasizing enrollment and retention strategies.
- Over 18 months, 712 participants were enrolled across 7 West African centers, with challenges including cultural understanding and the burdens of research participation.
- Positive enrollment factors included convenient visits and strong communication, leading to protocol changes like home visits and fewer blood draws to enhance participant satisfaction.
Background: Periodontal diseases are chronic and inflammatory in nature, and have been associated with hypertension, a major risk factor for cardiovascular diseases. Hypertension is prevalent among Nigerians. However, controlled studies on the relationship between hypertension and periodontal disease in Nigeria are limited.
View Article and Find Full Text PDFDespite positive economic forecasts, stable democracies, and reduced regional conflicts since the turn of the century, Africa continues to be afflicted by poverty, poor infrastructure, and a massive burden of communicable diseases such as HIV, malaria, tuberculosis, and diarrheal illnesses. With the rising prevalence of chronic kidney disease and kidney failure worldwide, these factors continue to hinder the ability to provide kidney care for millions of people on the continent. The International Society of Nephrology Global Kidney Health Atlas project was established to assess the global burden of kidney disease and measure global capacity for kidney replacement therapy (dialysis and kidney transplantation).
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- Lupus nephritis (LN) can lead to severe complications like kidney failure and death, with limited comparative data on treatment efficacy between mycophenolate mofetil (MMF) and intravenous cyclophosphamide (IVCYC) in African populations.
- A retrospective study in Cape Town analyzed 84 patients with biopsy-confirmed proliferative LN, finding no significant differences in remission or relapse rates after treatment with MMF or IVCYC, although baseline kidney function predicted mortality risk.
- The research indicates that both induction therapies yield comparable outcomes for patients in South Africa, but emphasizes the need for a prospective, randomized study for a more thorough evaluation of these treatments.
Background: The burden of symptoms and other concerns in chronic kidney disease (CKD) is known to be high, adversely affecting the quality of life of the growing number of those with this condition in developing countries. In this paper, we describe the protocol of a longitudinal observational study among people living with CKD. The study is developed to assess the bio-psychosocial factors associated with palliative care symptoms and concerns, and pattern of health services usage among Nigerians with stages 3-5 CKD.
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