[Effect of the antiserotoninergic preparation cyproheptadine on the levels of luteinizing and follicle-stimulating hormones and testosterone in patients with polycystic ovaries].

An antiserotoninergic drug cyproheptadine was administered to 10 patients at a dose of 4 mg per os to study LH, FSH and testosterone regulation in patients with polycystic ovaries. Blood samples were taken in the morning before, and 1 and 2 h after drug administration. A significant decrease in the level of testosterone (p less than 0.

[Diagnostic value of the luliberin test with patients with polycystic ovaries].

Gonadotropic function was investigated and the diagnostic value of the test with luteinizing hormone releasing factor (LHRF) was assessed in patients with polycystic ovaries. For this purpose a 100 micrograms dose of LHRF was intravenously jet injected to 10 patients with nonspecific polycystic ovaries. Levels of luteinizing and follicle stimulating hormones (LH and FSH) were determined before the injection and 15, 30, 60, 90 or 120 minutes after it.

[Lactotropic and thyrotropic functions of the hypophysis in polycystic ovary syndrome].

An increase in the prolactin basal level was detected in 8 out of 50 patients with ovarian polycystosis. A test with TRH and a simultaneous determination of the levels of prolactin, TTH, T3, T4 were used in 25 patients, of them a hyperergic reaction of prolactin to TRH was detected in 5. A correlation analysis of function of the thyroid was performed.