[Peri-infarct zone and the effect of mannitol on it].

Apart from clinical examination, blood enzyme activity was measured and ST intervals recorded on electrocardiotopograms (ECTG) from 35 leads in 56 patients (40 males and 16 females) with acute transmural anterior myocardial infarction. The osmotic diuretic mannitol was administered to 21 patients. The untreated patients were subdivided into 2 groups with respect to biochemical patterns they exhibited: enzyme activity peaking on Day 2 and coming back to normal by Day 7-10 (Group 1), and enzyme activity peaking on Day 3-4 and coming back to normal by Day 15-20 (Group 2).

[Cyclic adenosine monophosphate concentration in the blood plasma in coronary arteriosclerosis and its relationship to the nature of the metabolic disorders].

The concentrations of cyclic adenosine monophosphate (cAMP) in the blood plasma collected on an empty stomach were determined by the radiochemical method in 40 males from 37 to 72 years of age suffering from ischemic heart disease. The cAMP blood plasma content was significantly higher in patients with coronary atherosclerosis than in 20 healthy young persons of the control group. In patients with a diabetic character of the glycemic curve under conditions of the oral standard test for glucose tolerance, the concentration of cAMP in blood plasma was significantly higher than that in patients with normal or doubtful glycemic curves.

[Diagnosis of cardiomyopathy].

The problems of diagnosis of cardiomyopathies are discussed. Among 13 patients who died in the clinic, a correct diagnosis was made in 10. The observations permit to believe that cardiomyopathy is seen more often in males aged 41 to 55 years.