Zh Nevrol Psikhiatr Im S S Korsakova
October 2024
Objective: To search for neurophysiological correlates of the characteristics of the brain functional state in patients with endogenous depression with an ultra-high risk of developing psychosis in comparison with EEG parameters of patients without symptoms of a risk of developing psychosis and patients who have suffered psychotic episode.
Material And Methods: The study included 92 female patients, aged 16-26 years, at the stage of remission, divided into three groups: with depression without symptoms of ultra-high risk of developing psychosis (group 1, =42), with depression and attenuated psychotic symptoms, but without a history of a psychotic episode (group 2, =32) and with depression that developed after experiencing a psychotic episode (group 3, =18). In all patients, pre-treatment multichannel background EEG was recorded with spectral power analysis in narrow frequency sub-bands.