Publications by authors named "T I Moreva"

Article Synopsis
  • - Negative pressure breathing (NPBin) is a technique that lowers pressure in the respiratory tract during inhalation, aiming to boost blood flow to the heart and counteract fluid shifts in space.
  • - This study analyzed the effects of NPBin for 25 minutes at pressure reductions of -10 to -25 cmHO, using various non-invasive measurement techniques to assess changes in circulation and respiration in healthy volunteers.
  • - Results showed that NPBin increased tidal volume and decreased respiratory rate without significantly affecting overall minute ventilation, while circulatory parameters showed increased amplitude during breathing cycles, indicating a complex interaction between respiration and circulation.
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Cerebral blood flow and bioelectric activity were studied in 10 normal volunteers in order to assess cerebrovascular reactivity during different types of functional testing. The transcranial Doppler was used to measure linear blood velocity (LBV) in the middle cerebral artery (MCA) during maximal voluntary breath-holding (apnea), controlled verbal association test and tactile memory test. Simultaneous electroencephalography (EEG) registered the bioelectric activity of the brain cortex.

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This work was performed in hypertensive ISIAH and normotensive WAG rat strains. The latter was used as a control group. The general evaluation of behavior of the ISIAH and WAG rats tested in the open field, in the light-dark test, in the sound stress test, and in the fatigue test showed that the motor and exploratory activity provoked by an unfamiliar environment was much higher in the ISIAH rats as compared to the control WAG strain.

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Ultrasonic dopplerograpy of peripheral, including transcranial, blood circulation was performed in 8 normal volunteers for 7-day dry immersion experiment. Linear blood velocity (LBV) was measured in main arteries and veins of the head and lower extremities. Investigations were conducted on days 2 and 5 of immersion and on day 2 of recovery.

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NISAG rats with stress-induced arterial hypertension are characterized by hyperactivity of the sympathoadrenal system under rest conditions and during stress exposure.

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