The development, feasibility and acceptability of Empower-Autism: A new psychoeducational and psychotherapeutic programme for caregivers of children recently diagnosed with autism.

Parents and carers face many challenges following their child's autism diagnosis. They often look for information, and social and emotional support. There has been relatively little research into how best to provide this support and this means that there is no evidence to guide the delivery of services.

When to hold and when to fold: Early prediction of nonresponse to transcranial magnetic stimulation in major depressive disorder.

Background: Determining when to recommend a change in treatment regimen due to insufficient improvement is a common challenge in therapeutics.

Methods: In a sample of 7215 patients with major depressive disorder treated with transcranial magnetic stimulation (TMS) and with PHQ-9 scores before, during and after the course, 3 groups were identified based on number of acute course sessions: exactly 36 sessions (N = 3591), more than 36 sessions (N = 975), and less than 36 sessions (N = 2649). Two techniques were used to determine thresholds for percentage change in PHQ-9 scores at assessments after 10, 20, and 30 sessions that optimized prediction of endpoint response status: the Youden index and fixing the false positive rate at 10%.

Comparison of a Daily Steviol Glycoside Beverage compared with a Sucrose Beverage for Four Weeks on Gut Microbiome in Healthy Adults.

Background: Recent studies suggest that some nonnutritive sweeteners (NNS) have deleterious effects on the human gut microbiome (HGM). The effect of steviol glycosides on the HGM has not been well studied.

Objective: We aimed to evaluate the effects of stevia- compared with sucrose-sweetened beverages on the HGM and fecal short-chain fatty acid (SCFA) profiles.

Characterisation of neutron fields at the n-lab, a fast neutron facility at the University of Cape Town.

The n-lab is a fast neutron facility based in the Department of Physics, University of Cape Town, offering collimated neutron beams produced by an MP 320 deuterium-tritium sealed tube neutron generator, and a 220 GBq americium-beryllium radioisotopic source. Characterisations of the spatial and energy distributions of the fast neutron beams were performed using an EJ-301 organic liquid scintillator detector and digital data acquisition system. Neutron energy spectra were obtained through unfolding analyses with MAXED, and a Monte Carlo approach to the propagation of uncertainties was implemented.

Survey of staff experiences of potential stigma during the COVID19 pandemic.

The impact of COVID-19 on everyone's lives has been significant. However, there is also another factor related to the well-being of healthcare workers (HCWs) and that is how they are perceived by the general public. The aim of this study is to provide insight into the scope of this potential problem and describe how HCWs perceive community views and if this influences provision of patient care.