Publications by authors named "T Horikawa"
Aberrant immune responses to viral pathogens contribute to pathogenesis, but our understanding of pathological immune responses caused by viruses within the human virome, especially at a population scale, remains limited. We analyzed whole-genome sequencing datasets of 6,321 Japanese individuals, including patients with autoimmune diseases (psoriasis vulgaris, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), pulmonary alveolar proteinosis (PAP) or multiple sclerosis) and coronavirus disease 2019 (COVID-19), or healthy controls. We systematically quantified two constituents of the blood DNA virome, endogenous HHV-6 (eHHV-6) and anellovirus.
View Article and Find Full Text PDFProblem: To identify the predictive factors for the recurrence of chronic endometritis (CE) in infertile women.
Method Of Study: In this case-control study, 1170 infertile women recovered from CE and underwent fertility treatment between December 2018 and August 2021. Among the 146 women (12.
Article Synopsis
- Hypertensive emergencies can lead to serious organ damage, and this study aimed to investigate the role of the renin-angiotensin-aldosterone system (RAS) in such cases.
- The study included 63 patients with severe hypertension and various organ injuries, assessing their blood pressure and aldosterone levels.
- Results showed that higher aldosterone levels were linked to more organ damage and complications, suggesting that RAS plays a significant role in affecting patient outcomes during hypertensive emergencies.
Background: Oral hypofunction is the stage before oral dysfunction. The subjective symptoms of poor oral function and the decline in oral health-related quality of life (OHRQoL) that occur in the oral hypofunction stage can be missed.
Objective: This multicentre cross-sectional study was performed to examine the relationships between the test results for oral hypofunction, subjective frailty symptoms and OHRQoL of outpatients in dental clinics.