Publications by authors named "T Hirota"
Background: Allergic diseases are major causes of morbidity in both developed and developing countries and represent a global burden on health care systems. Allergic sensitization is defined as the production of immunoglobulin E (IgE) specific to common environmental allergens, and it is an important indicator in the assessment of allergic diseases.
Objectives: This study aimed to clarify the genetic basis of allergic sensitization.
Introduction: Mitral regurgitation is a potential complication of transcatheter aortic valve replacement. Here, we report a case of severe acute mitral regurgitation caused by papillary muscle rupture occurring 16 days after transcatheter aortic valve replacement.
Presentation Of Case: An 82-year-old woman with severe AS was referred to our hospital.
To clarify the adaptation strategies of cold-tolerant wheat against global warming, this study examined the effects of daily temperature, precipitation, and sunshine duration on wheat yield in Hokkaido, Japan, over 13 years (2011-2023). Yield components were also analyzed over 20 years (2004-2023). The number of snow-cover days decreased by about 24 days over the 20-year period.
View Article and Find Full Text PDFResident memory B cells are enriched in chronic rhinosinusitis with nasal polyps.
J Allergy Clin Immunol Glob
February 2025
Article Synopsis
- Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition affecting the nasal passages, and this study aims to analyze specific memory B-cells (BRM) in this context.
- Researchers found that while BRM cells exist in normal sinonasal tissue, their presence is much more pronounced in nasal polyps from CRSwNP patients, as shown through advanced laboratory techniques.
- This discovery could enhance understanding of immune responses in CRSwNP and pave the way for new treatments, including therapies targeting B-cells.