Publications by authors named "T Hirashima"
Constitutional indocyanine green (ICG) excretion defect (CIED) is a rare clinical condition characterized by markedly delayed ICG disappearance with other normal liver function tests. Here, we report a case of CIED in which laparoscopic anatomical liver resection was successfully performed using ICG fluorescence staining. A 64-year-old man with a 4-cm tumor located in the liver segment 5 was referred to our hospital.
View Article and Find Full Text PDFMammalian sperm cells travel from their origin in the male reproductive tract to fertilization in the female tract through a complex process driven by coordinated mechanical and biochemical mechanisms. Recent experimental and theoretical advances have illuminated the collective behaviors of sperm both in vivo and in vitro. However, our understanding of the underlying mechano-chemical processes remains incomplete.
View Article and Find Full Text PDFMorphogens, locally produced signaling molecules, form a concentration gradient to guide tissue patterning. Tissue patterns emerge as a collaboration between morphogen diffusion and responsive cell behaviors, but the mechanisms through which diffusing morphogens define precise spatial patterns amidst biological fluctuations remain unclear. To investigate how cells respond to diffusing proteins to generate tissue patterns, we develop SYMPLE3D, a 3D culture platform.
View Article and Find Full Text PDFArticle Synopsis
- Chloroplasts in different species, like Chlamydomonas reinhardtii and C. applanata, exhibit complex shapes such as cup-like forms and starfish-like structures, challenging the traditional view that they are merely spheroid.
- Advanced imaging techniques revealed that C. reinhardtii chloroplasts have features like large and small holes that aid in metabolite transport, along with an increase in volume under certain conditions.
- The study suggests a need to rethink our understanding of chloroplast morphology and evolution, moving away from the idea that chloroplasts are uniform in shape and closely resembling cyanobacteria.
Objective: The objective of this study was to provide a convenient preoperative prediction of the risk of early postoperative mortality.
Materials And Methods: This retrospective study included patients who underwent surgery for spinal metastasis at our hospital between 2009 and 2021. Preoperative blood test data of all patients were collected, and the survival time was calculated by dividing the blood data.