Pathogenic/Likely Pathogenic Variant Patients with Breast, Ovarian, and Other Cancers.

The demographic and clinical characteristics of patients who have pathogenic/likely pathogenic variants may differ from their relatives who had related cancer. In this study, we aimed to demonstrate the clinical and demographic findings of patients who had -related cancer and to assess the differences comparing their relatives who had -related cancer with breast, genital tract, prostate, and pancreas cancers as well. The results of sequencing analysis of 200 cancer patients (190 women, 10 men) who have been directed to genetic counseling with an indication of testing from different regions across 9 medical oncology centers were retrospectively analyzed.