Basic fibroblast growth factor loaded polypropylene meshes in repair of abdominal wall defects in rats.

Background And Aim: Incisional hernia following laparotomy and recurrent herniation after its repair are still common problems in spite of mesh augmentation. The underlying biological mechanism may be related to collagen metabolism. Recently, some members of growth factors family have been tested in the prevention of wound failure and incisonal hernia formation.