Publications by authors named "T Hardcastle"

Background: Serum albumin levels decrease following major trauma, for various reasons. We postulated that the serum albumin nadir (SAN) level would correlate negatively with severity of physiological insult.

Methodology: This retrospective cohort study included all patients with abdominal trauma admitted to the Trauma Intensive Care Unit at Inkosi Albert Luthuli Central Hospital during 2017 and 2018.

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Article Synopsis
  • * A retrospective review of trauma ICU patients from 2013 to 2022 revealed that out of 2805 patients, 153 had vascular injuries, with fractures being the most common associated injury.
  • * The findings suggest that both the type of vascular injury and any additional injuries significantly impact patient outcomes, underscoring the importance of a multidisciplinary approach to treatment.
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Purpose: Adequate access to antiretrovirals (ARV) has improved the longevity and quality of life of people living with the human immunodeficiency virus(HIV). Antiretrovirals are known to cause multiple drug-drug interactions. It was noted clinically that patients on ARVs appeared to be more difficult to sedate.

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