Publications by authors named "T Hagi"
DNA methylation is known to be involved in tumor progression. This is the first study to perform an extensive methylation analysis of plasma circulating tumor DNA (ctDNA) using targeted bisulfite sequencing in gastric cancer (GC) patients to evaluate the usefulness of ctDNA methylation as a new biomarker. Sixteen patients who received chemotherapy for recurrent GC were included.
View Article and Find Full Text PDFBackground/aim: Cryoablation is a new, minimally invasive option for local tumor therapy that is attracting attention due to its potential interactions with the immune system. The purpose of this study was to evaluate the efficacy of cryoablation for local control of bone and soft tissue lesions, to elucidate risk factors for recurrence, and to clarify histological changes.
Patients And Methods: Participants comprised 25 patients who underwent cryoablation for 53 discrete lesions of bone or soft tissue recurrence after resection or as metastases of cancer or sarcoma.
Article Synopsis
- Osteochondromas are benign growths typically found in the long bones' metaphyseal region, with a very low risk of turning malignant, although cases of transformation to osteosarcoma are rare.
- A 66-year-old woman experienced abdominal pain leading to the discovery of osteosarcoma derived from osteochondromas in her right iliac bone; after chemotherapy and surgical removal, pathology confirmed the diagnosis.
- Three years post-surgery, the patient showed no signs of cancer recurrence or metastasis and regained the ability to walk unaided, but ongoing monitoring is advised.
Introduction: This study aimed to evaluate the efficacy of perioperative dysphagia rehabilitation in older adult patients diagnosed with gastric cancer who underwent gastrectomy.
Materials And Methods: This retrospective study included 149 patients over 80 years who underwent gastrectomies between January 2000 and December 2020. The patients were divided into two groups based on the intervention of the dysphagia rehabilitation team (DRT group: n = 101) and the non-intervention control group (C group: n = 48).
Article Synopsis
- Malignant chest wall tumors require extensive resection and careful reconstruction, using vascularized tissue for both soft tissue and bone defects, with this study assessing how different reconstruction strategies impact complications.
- The research analyzed data from 45 patients who underwent 52 operations, categorizing tumors into superficial and deep types and examining outcomes based on the chosen reconstruction method.
- Results showed a local recurrence-free survival rate of 83.9% at 5 years, but a surgical complication rate of 11.5%, notably higher in deep tumors that required flap transfers, with these strategies being key risk factors for complications.