Study Objectives: Rates of cannabis use disorder (CUD) appear to be increasing nationally, with increases greater in states that legalized cannabis use. However, as legalization has progressed and stigma declined, some of these apparent increases could be due to greater willingness of survey respondents and patients to acknowledge cannabis involvement. Biological indicators of cannabis use overcome some concerns about trends denoted by self-report data whose validity is potentially changing over time.
View Article and Find Full Text PDFIntroduction: More men have substance use disorders (SUD) in the US compared to women; however, the gender gap is closing, including among US veterans. Little information is available about gender differences in patterns of SUD treatment receipt. The current study evaluated gender differences in SUD outpatient, residential, and medication treatment receipt to address critical gaps in the literature.
View Article and Find Full Text PDFComp Biochem Physiol C Toxicol Pharmacol
June 2025
Cobalt, a metallic element found naturally in the earth's crust, is essential to survival. It is the active center of cobalamins such as vitamin B12 and is also a micronutrient for bacteria, algae, and fungi. The effects of cobalt (II) chloride (CoCl), the inorganic form of cobalt, are dependent on the dosage.
View Article and Find Full Text PDFThe Strategy Use Measure (SUM) was developed as a systematic tool to assess cognitive, behavioural and emotional strategy use by clients and carers after acquired brain injury. Comprehensive content development was undertaken across four clinical service sites via expert clinician consultation and consensus, file review of strategies used in clinical practice, and consumer consultation. Statistical analysis was undertaken to evaluate items and assess reliability, validity and factor structure.
View Article and Find Full Text PDFBackground: Immune effector cell-associated neurotoxicity syndrome (ICANS) is a common complication of chimeric antigen receptor (CAR) T-cell therapy. Current practice guidelines recommend the immune effector cell-associated encephalopathy (ICE) score for the assessment and monitoring of ICANS.
Objective: To demonstrate modifications to ICE score to patients with vision and hearing impairments or who are who are from non-native-speaking backgrounds.