Publications by authors named "T H Sander"

Article Synopsis
  • Dystonia is a movement disorder linked to an imbalance in brain pathways involving the striatum and internal pallidum, but its neuronal causes are not fully understood.
  • This study conducted invasive recordings from ten dystonia patients using deep brain stimulation electrodes to observe brain activity across different basal ganglia nuclei.
  • Findings showed that low-frequency brain activity between the striatum and internal pallidum correlates with the severity of dystonic symptoms, highlighting the importance of the direct striato-pallidal pathway in the disorder's development.
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Magnetoencephalography (MEG) allows the non-invasive measurement of brain activity at millisecond precision combined with localization of the underlying generators. So far, MEG-systems consisted of superconducting quantum interference devices (SQUIDS), which suffer from several limitations. Recent technological advances, however, have enabled the development of novel MEG-systems based on optically pumped magnetometers (OPMs), offering several advantages over conventional SQUID-MEG systems.

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Knowledge about the 3-dimensional structure, orientation and interaction of chemical compounds is important in many areas of science and technology. X-ray crystallography is one of the experimental techniques capable of providing a large amount of structural information for a given compound, and it is widely used for characterisation of organic and metal-organic molecules. The method provides precise 3D coordinates of atoms inside crystals, however, it does not directly deliver information about certain chemical characteristics such as bond orders, delocalization, charges, lone electron pairs or lone electrons.

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Purpose: Fasting guidelines for children recommend restricting clear fluids for one or two hours before a procedure to reduce pulmonary aspiration. Gastric volumes < 1.5 mL·kg do not seem to present an increased risk of pulmonary aspiration.

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