Publications by authors named "T H Rainer"
Sophora alkaloids, including matrine, oxymatrine, and sophoridine, are quinolizidines found in plants used in traditional Chinese medicine such as Sophora flavescens and Sophora tonkinensis. Reports on acute Sophora alkaloid poisoning in humans outside of mainland China are lacking. This study aimed to characterize the clinical presentations, management, and outcomes of acute poisoning involving Sophora alkaloids in Hong Kong.
View Article and Find Full Text PDFThis is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and risks of early versus late initiation of oral anticoagulation (vitamin K antagonists or NOACs) in people with non-valvular atrial fibrillation-related ischaemic stroke.
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- The study investigated how methyl salicylate levels in the blood change after ingestion, aiming to identify peak serum concentrations and factors influencing these levels.
- Researchers analyzed cases from the Hong Kong Poison Control Centre involving 41 patients, finding that the median time to peak concentration was 5.6 hours, with gastric aspiration and activated charcoal use being linked to lower peak levels.
- Results suggest that the peak concentration of serum salicylate occurs slower than previously thought, indicating the need for ongoing monitoring in patients after ingestion.
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- Health disparities in critically ill children have mostly been examined within individual ICU types, limiting broader collaboration to improve care.
- This scoping review aims to summarize existing research on health disparities across three main ICU settings: neonatal, pediatric, and cardiac ICUs in the United States.
- The review includes over 50 studies that highlight disparities based on race, ethnicity, insurance status, socioeconomic factors, language, and geographic distance.
Article Synopsis
- Cocaine when used with ethanol leads to the creation of cocaethylene, which has a longer effect; this study investigates the combined toxicity of these substances in Hong Kong.
- A retrospective study analyzed 109 patients who had acute cocaine toxicities, confirming ethanol co-ingestion through blood tests in some cases.
- Contrary to earlier studies, results indicated that using cocaine and ethanol together is linked to a lower risk of serious adverse outcomes compared to using cocaine alone.