Publications by authors named "T H Osborne"

Background: The intrauterine device (IUD) is a highly effective form of long-acting reversible contraception, widely recognized for its convenience and efficacy. Despite its benefits, many patients report moderate to severe pain during and after their IUD insertion procedure. Furthermore, reports suggest significant variability in pain control medications, including no adequate pain medication.

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We present a quantum-classical algorithm to study the dynamics of the Rohksar-Kivelson plaquette ladder on NISQ devices. We show that complexity is largely reduced using gauge invariance, additional symmetries, and a crucial property associated to how plaquettes are blocked against ring-exchange in the ladder geometry. This allows for an efficient simulation of sizable plaquette ladders with a small number of qubits, well suited for the capabilities of present NISQ devices.

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Article Synopsis
  • COVID-19 survivors, particularly older adults, experience increased frailty, which can lead to new medical conditions and functional impairments.
  • A study involving over 91,000 older Veterans showed that those who had COVID-19 developed significantly more health deficits in the year following infection compared to uninfected controls.
  • The most common new health issues identified were fatigue, anemia, muscle atrophy, gait abnormalities, and arthritis, indicating long-term health risks associated with COVID-19.
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  • β-adrenergic (β-AR) signaling triggers fight-or-flight responses, enhancing functions like heart and lung performance, metabolism, and muscle contraction.
  • Recent studies challenge the traditional view of β-AR signaling as short-lived, revealing its role in long-term effects like cell differentiation and epigenomic changes.
  • The chapter examines how cold stress influences adipose tissues through β-AR signaling, emphasizing the dual role of the histone demethylase JMJD1A in managing both immediate and prolonged thermogenic responses.
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