Comparing Self-Perceived Awareness to Actual Awareness of the Podiatric Profession Among High School and College Students.

Background: Over the past few years there has been a decrease in the number of applicants applying to podiatric medical school. It has been suggested that this may be due to unfamiliarity with the profession of podiatric medicine. The goal of this study is to shed light on the misconceptions and lack of awareness of podiatric medicine so that the profession can better bridge the gap in knowledge with a resultant strategy to better increase recruiting efforts.

Cardiotoxic Effects Following CAR-T Cell Therapy: A Literature Review.

Purpose Of Review: This paper reviewed the current literature on incidence, clinical manifestations, and risk factors of Chimeric Antigen Receptor T-cell (CAR-T) cardiotoxicity.

Recent Findings: CAR-T therapy has emerged as a groundbreaking treatment for hematological malignancies since FDA approval in 2017. CAR-T therapy is however associated with a few side effects, among which cardiotoxicity is of significant concern.

Three-dimensional linkage analysis with digital PCR for genome integrity and identity of recombinant adeno-associated virus.

Recombinant adeno-associated virus (rAAV) has emerged as the vector of choice for in vivo gene delivery, with numerous clinical trials underway for the treatment of various human diseases. Utilizing rAAV in gene therapy requires a highly precise quantification method to determine the viral genome titer and further establish the optimal therapeutic dosage for a rAAV product. The conventional single-channel droplet digital PCR (1D ddPCR) method offers only partial information regarding the viral vector genome titer, lacking insights into its integrity.

Bilateral breast swelling in a pregnant woman with high-grade B-cell lymphoma, potentially Burkitt lymphoma.

Primary breast Burkitt lymphoma is an aggressive subtype of non-Hodgkin lymphoma (NHL) and extremely rare. Burkitt lymphoma involving both breasts during pregnancy was a rare condition with fifteen cases reported in literature. We present a case of a 19-year-old 36 weeks pregnant woman who came for a check-up due to bilateral breast swelling.

Interventions for Type 2 Diabetes Prevention and Management Among Indigenous Children and Youth: A Systematic Review.

Introduction: Indigenous populations experience a disproportionately higher burden of early onset of type 2 diabetes mellitus (T2DM). To contribute towards addressing this health disparity, evidence-based culturally appropriate interventions are urgently needed. This systematic review examines interventions designed to improve the prevention and management of T2DM among Indigenous children and youth.