Publications by authors named "T H Gee"
Background: Weight-class athletes commonly engage in rapid weight loss (RWL) practices.
Aim: Investigate attributed RWL perceptions and thoughts of UK-based Olympic weightlifters.
Methods: Participants (n: 39, male: 22, female: 17) were selected from International Weightlifting Federation populations, 85% had previously acutely reduced pre-competition body mass.
Endocannabinoid involvement in beneficial effects of caloric restriction in a rodent model of comorbid depression and epilepsy.
Prog Neuropsychopharmacol Biol Psychiatry
December 2024
Clinically, patients with depression are at a heightened risk for developing epilepsy, and vice versa, suggesting shared mechanisms for this bidirectional comorbidity. Unfortunately, comorbid depression and epilepsy is associated with worsened quality of life and treatment refractoriness, highlighting the need for novel treatment targets and nonpharmacologic supplements to existing therapies. The present study used the Swim-Low Active rat, a well-validated model of depression and epilepsy comorbidity that was selectively bred based on forced swim test behavior, to assess the safety and efficacy of caloric restriction in treating this comorbidity.
View Article and Find Full Text PDFBackground: Predicting fibrostenotic complications prior to endoscopy in eosinophilic esophagitis (EoE) is challenging and esophageal strictures and narrowing are commonly missed on endoscopy.
Aim: To develop and validate a score to predict fibrostenosis in EoE patients prior to endoscopy.
Methods: We leveraged a large database of newly diagnosed EoE patients.
Daily or Twice Daily Treatment with Topical Steroids Results in Similar Responses in Eosinophilic Esophagitis.
Clin Gastroenterol Hepatol
November 2024
Background & Aims: Few data compare topical corticosteroid (tCS) dosing regimens and outcomes. We aimed to compare treatment outcomes in patients with eosinophilic esophagitis (EoE) by once or twice daily dosing regimens.
Methods: We conducted a retrospective cohort study using the UNC EoE Clinicopathologic Database of newly diagnosed patients with EoE treated with a tCS who had a follow-up endoscopy with biopsy.
Article Synopsis
- Cannabis use is rising among people for both recreational and medical reasons, but there isn't much research on its effects in eosinophilic esophagitis (EoE).
- A study involved 983 newly diagnosed EoE patients, with 80 reporting cannabis use, mainly through inhalation and daily consumption.
- Findings indicated that cannabis users had milder initial symptoms but showed worse inflammatory responses after treatment compared to non-users, suggesting that cannabis may negatively affect EoE management.