The impact of age on rectal cancer treatment, complications and survival.

Background: The number of older patients with rectal cancer is increasing. Treatment outcome discrepancies persist, despite similar treatment guidelines. To offer the oldest patients optimal individually adjusted care, further knowledge is needed regarding treatment strategy and outcome.

Risk factors for right colon, left colon and rectal cancers differ between men and women: the population-based HUNT study in Norway.

Aim: The aim of this study was to assess established risk factors for colorectal cancer (CRC) separately for right colon, left colon and rectal cancer in men and women.

Method: This was a prospective cohort study comparing incidental CRC cases and the general population participating in a longitudinal health study in Norway (the HUNT study).

Results: Among 78 580 participants (36 825 men and 41 754 women), 1827 incidental CRCs were registered (931 men and 896 women).

Octogenarian patients with colon cancer - postoperative morbidity and mortality are the major challenges.

Background: Few studies have addressed colon cancer surgery outcomes in an unselected cohort of octogenarian patients. The present study aimed to evaluate the relative survival of octogenarian patients after a major resection of colon cancer with a curative intent.

Methods: All patients diagnosed with colon cancer at Levanger Hospital between 1980 and 2016 were included.

Long-term trends in colorectal cancer: incidence, localization, and presentation.

Background: The purpose of this study was to assess trends in incidence and presentation of colorectal cancer (CRC) over a period of 37 years in a stable population in Mid-Norway. Secondarily, we wanted to predict the future burden of CRC in the same catchment area.

Methods: All 2268 patients diagnosed with CRC at Levanger Hospital between 1980 and 2016 were included in this study.

Epidemiology of perforating peptic ulcer: A population-based retrospective study over 40 years.

Background: The incidence of peptic ulcer disease has decreased during the last few decades, but the incidence of reported peptic ulcer complications has not decreased. Perforating peptic ulcer (PPU) is a severe form of the disease.

Aim: To assess trends in the incidence, presentation, and outcome of PPU over a period of 40 years.