The Early Access and the Potential Cost Savings by the Compassionate Use of Onco-haematological Drugs: Results from the Italian Study Compass-O.

Background: Compassionate drug use (CDU) provides early access to not yet authorised medicines and is funded by pharmaceutical companies. The observational retrospective study Compass-O monitored the CDU of onco-haematological drugs, managed by seven Italian units for cytotoxic drug preparations (Unità Farmaci Antiblastici [UFA]), between 1 January, 2016 and 31 December, 2021.

Objective: We aimed to evaluate the CDU of onco-haematological drugs managed by seven Italian UFA, between 2016 and 2021.

Impact of reducing nitrate/nitrite levels on the behavior of Salmonella Typhimurium and Listeria monocytogenes in French dry fermented sausages.

Salmonella and Listeria monocytogenes are two pathogenic bacteria that most frequently contaminate pork meat. In dry fermented sausages, several hurdles are used for controlling bacterial growth such as nitrite and salt addition. In Europe, practices consist of adding potassium nitrate (250ppm expressed as NaNO) or a combination of nitrate/nitrite (150/150ppm expressed as NaNO/NaNO respectively).

TRUNCATION ARTIFACT IN MAGNETIC RESONANCE IMAGES OF THE CANINE SPINAL CORD.

The truncation artifact in magnetic resonance (MR) images is a line of abnormal signal intensity that occurs parallel to an interface between tissues of markedly different signal intensity. In order to demonstrate the truncation artifact in sagittal images of the canine spinal cord and the effect of changing spatial resolution, we conducted an experimental in vitro study. A section of fixed canine spinal cord was imaged using a 1.

Description and evaluation of four ultrasound-guided approaches to aid spinal canal puncture in dogs.

Objective: To describe four ultrasound-guided approaches to the lumbar and thoracic spine to aid spinal canal puncture in the dog and to evaluate the feasibility of the technique.

Study Design: Prospective experimental study.

Animal Population: Two canine cadavers.

A description of a technique for ultrasound-guided lumbar plexus catheter in dogs: cadaveric study.

Objective: To describe an ultrasound-guided approach for lumbar plexus catheter placement in dogs.

Study Design: Prospective experimental cadaveric study.

Animals: Eleven thawed canine cadavers (13 ± 2 kg).