The efficient magneto-mechanical actuation of cancer cells using a very low concentration of non-interacting ferrimagnetic hexaferrite nanoplatelets.

Magneto-mechanical actuation (MMA) using the low-frequency alternating magnetic fields (AMFs) of magnetic nanoparticles internalized into cancer cells can be used to irreparably damage these cells. However, nanoparticles in cells usually agglomerate, thus greatly augmenting the delivered force compared to single nanoparticles. Here, we demonstrate that MMA also decreases the cell viability, with the MMA mediated by individual, non-interacting nanoparticles.

Magneto-mechanical actuation of barium-hexaferrite nanoplatelets for the disruption of phospholipid membranes.

Hypothesis: The magneto-mechanical actuation (MMA) of magnetic nanoparticles with a low-frequency alternating magnetic field (AMF) can be used to destroy cancer cells. So far, MMA was tested on different cells using different nanoparticles and different field characteristics, which makes comparisons and any generalizations about the results of MMA difficult. In this paper we propose the use of giant unilamellar vesicles (GUVs) as a simple model system to study the effect of MMA on a closed lipid bilayer membrane, i.

Inherent Surface Properties of Adsorbent-Free Ultrathin BiSe Topological Insulator Platelets.

We report on a hydrothermal synthesis of hexagonal ultra-thin BiSe platelets, which was performed without any organic reactants. The synthesis resulted in the particles with a surface, clean of any organic adsorbents, which was confirmed with a high-resolution transmission electron microscopy, zeta-potential measurements and thermogravimetric measurements coupled with a mass spectroscopy. Due to the absence of the adsorbed organic layer on the BiSe platelet surface, we were able to measure their inherent surface and optical properties.

Discrete evolution of the crystal structure during the growth of Ba-hexaferrite nanoplatelets.

An understanding of the adaptation of the crystal structure of materials confined at the nanoscale, the influences of their specific structures on the evolution of their morphologies and, finally, their functional properties is essential not only for expanding fundamental knowledge, but also for facilitating the designs of novel nanostructures for diverse technological and medical applications. Here we describe how the distinct structure of barium-hexaferrite nanoplatelets evolves in a stepwise manner in parallel with the development of their size and morphology during hydrothermal synthesis. The nanoplatelets are formed by reactions between Ba- and Fe-hydroxides in an aqueous suspension at temperatures below 80 °C.

Novel Ba-hexaferrite structural variations stabilized on the nanoscale as building blocks for epitaxial bi-magnetic hard/soft sandwiched maghemite/hexaferrite/maghemite nanoplatelets with out-of-plane easy axis and enhanced magnetization.

Atomic-resolution scanning-transmission electron microscopy showed that barium hexaferrite (BHF) nanoplatelets display a distinct structure, which represents a novel structural variation of hexaferrites stabilized on the nanoscale. The structure can be presented in terms of two alternating structural blocks stacked across the nanoplatelet: a hexagonal (BaFeO) R block and a cubic (FeO) spinel S block. The structure of the BHF nanoplatelets comprises only two, or rarely three, R blocks and always terminates at the basal surfaces with the full S blocks.