Publications by authors named "T Gorgiladze"

Article Synopsis
  • The study aimed to examine oral mucosa diseases in COVID-19 patients from the Adjara region, involving 55 participants with varying severity of infection.
  • Findings revealed that 40% of patients had oral lesions, with common issues being candidiasis and ulcers, as well as altered taste and other symptoms.
  • This research is the first of its kind in the Adjara region, providing valuable insights into oral health complications linked to COVID-19.
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Objective: To analyse the methylation status of the Long Interspersed Nuclear Element-1 (LINE-1) and Short Interspersed Nuclear Element Alu (Alu) of peripheral blood mononuclear cells (PBMCs) from patients with migraine compared with healthy control subjects.

Methods: This case-control study recruited patients with migraine without aura and age-matched healthy control subjects. PBMCs were purified from peripheral blood samples.

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It has been established that the midbrain periaqueductal gray matter (PAG) and rostral ventro-medial medulla (RVM) are involved in the descending pain control system. The latter involves the midline nucleus raphe magnus (NRM) and adjacent reticular formation. These brain structures are is one of important parts of CNS circuit that controls nociceptive transmission at the level of spinal cord.

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The paper analyses results after experimental studies of effectiveness of medical forms of fibronectin used in a form of eye drops for treatment of infectious keratitis on a model of bacterial corneal ulcer in 30 rabbits (60 eyes). The results obtained speak about a pronounced stimulating action of fibronectin on reparative processes: almost a twice quicker epithelialization of corneal defects (by 46.8%) and a quicker reverse development of inflammatory signs as compared with the control group of animals.

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