Publications by authors named "T Gonzalez-Alujas"
Objectives: Partial thrombosis of the false lumen (FL) in patients with chronic aortic dissection (AD) of the descending aorta has been associated with poor outcomes. Meanwhile, the fluid dynamic and biomechanical characteristics associated with partial thrombosis remain to be elucidated. This retrospective, single-center study tested the association between FL fluid dynamics and biomechanics and the presence and extent of FL thrombus.
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- Percutaneous mitral paravalvular leak (PVL) closure is a safe and effective alternative to surgery, but its long-term outcomes are not well-studied. The study focused on how successful closure impacts long-term patient outcomes.* -
- Researchers analyzed data from 90 patients undergoing their first mitral PVL closure attempt between 2010 and 2021, finding that while 91.1% had a reduction in leak severity, only 52.2% achieved successful closure.* -
- After a median follow-up of 3.2 years, those with procedural failure faced significantly higher mortality rates, particularly from cardiovascular causes, indicating that successful PVL closure greatly benefits long-term health.*
Aims: To assess the progression of the disease and evolution of the main echocardiographic variables for quantifying AS in patients with severe low-flow low-gradient (LFLG) AS compared to other severe AS subtypes.
Methods And Results: Longitudinal, observational, multicenter study including consecutive asymptomatic patients with severe AS (aortic valve area, AVA < 1.0 cm²) and normal left ventricle ejection fraction (LVEF ≥ 50%).
Background: Atrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic strokes. We aimed to test the usefulness of candidate blood-biomarkers related to AF pathophysiology in two prospective cohorts representative of those populations.
Methods: Two hundred seventy-four subjects aged 65-75 years with hypertension and diabetes from the AFRICAT cohort, and 218 cryptogenic stroke patients aged >55 years from the CRYPTO-AF cohort were analyzed.
Objectives: To determine the risk of mortality and need for aortic valve replacement (AVR) in patients with low-flow low-gradient (LFLG) aortic stenosis (AS).
Methods: A longitudinal multicentre study including consecutive patients with severe AS (aortic valve area [AVA] < 1.0 cm) and normal left ventricular ejection fraction (LVEF).