Publications by authors named "T Goi"
Aim: The Japanese National Clinical Database, which covers more than 95% of the surgeries performed in Japan, is the largest nationwide database. This is the 2021 annual report of the Gastroenterological Section of the National Clinical Database, which aims to present the short-term outcomes of cases registered in 2021 and discuss significant changes and insights into gastroenterological surgeries observed over the decade.
Methods: We reviewed the data of patients registered in the National Clinical Database between 2012 and 2021.
Background: Type 2 autoimmune pancreatitis is characterized by multiple or segmental strictures of the main pancreatic duct without upstream dilatation. We encountered a case of mass-forming type 2 autoimmune pancreatitis with upstream main pancreatic duct dilatation that was difficult to diagnose preoperatively using endoscopic ultrasound sonography-guided fine-needle aspiration cytology.
Case Presentation: A 58-year-old Japanese man presented with recurrent acute pancreatitis secondary to a 10-mm pancreatic head tumor.
Reduction of Blood Oxidative Stress Following Colorectal Cancer Resection.
Cancers (Basel)
October 2024
Background: Colorectal cancer is a major global health burden, with surgical resection being the standard treatment aimed at curative tumor removal. Oxidative stress plays a crucial role in colorectal cancer progression and prognosis. This study hypothesized that physical removal of colorectal cancer, a primary source of oxidative stress, would reduce blood levels of reactive oxygen metabolite derivatives (d-ROMs), a marker of oxidative stress, and biologic antioxidant potential (BAP) levels, a marker of antioxidant potential.
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- Vitamin B12 deficiency can lead to serious health issues, including macrocytic anemia and mental disorders, and its diagnosis can be challenging.
- A case study reports a 37-year-old woman experiencing psychiatric symptoms after total gastrectomy due to impaired absorption of vitamin B12, which was verified by low blood levels of the vitamin.
- The patient showed rapid improvement after starting vitamin B12 supplementation, highlighting the need to consider this deficiency in patients with a history of gastric surgery when they present with unexplained mental health changes.
Article Synopsis
- Circulating tumor cells (CTCs) are cancer cells that can enter the bloodstream and are linked to cancer progression, recurrence, and metastasis, particularly in colorectal cancer (CRC).
- A study examined the role of CD44v9 expression in CTCs and preoperative carcinoembryonic antigen (CEA) levels among 300 CRC patients, finding that 31.3% showed CD44v9 mRNA expression, which correlated with liver metastasis.
- Results indicated that patients with positive CD44v9 expression had a significantly lower 5-year survival rate compared to those without it, suggesting that both CD44v9 expression and CEA levels could serve as important prognostic indicators for CRC.