A Multicenter, Randomized, Observer-blinded, Active-controlled Study Evaluating the Safety and Effectiveness of Ceftaroline Compared With Ceftriaxone Plus Vancomycin in Pediatric Patients With Complicated Community-acquired Bacterial Pneumonia.

Background: The broad-spectrum cephalosporin ceftaroline, a metabolite of the prodrug ceftaroline fosamil, has shown in vitro activity against clinical isolates from pediatric patients.

Methods: This multicenter, randomized, observer-blinded, active-controlled study (NCT01669980) assessed the safety and effectiveness of ceftaroline fosamil compared with ceftriaxone plus vancomycin in patients between 2 months and 17 years of age with complicated community-acquired bacterial pneumonia. Patients were randomized 3:1 (stratified by age cohort) to receive either ceftaroline fosamil or ceftriaxone plus vancomycin (comparator) as intravenous therapy for ≥3 days.

Influence of ferrotherapy on psychomotor development of children of yearly age with iron deficiency anemia.

According to universally acknowledged biopsychosocial model of development, numerous biological and environmental factors influence development of children. One of them is iron deficiency in the organism. The study assessed physical, motor and psychosocial development of children who at an early age had the diagnosis of iron deficiency anemia and had been treated by iron drugs.

Encephalocele and skeletal malformations (case report).

Encephalocele is a herniation of the brain (cranium bifidum, cephalocele, craniocele), formed during embryonic development, because of the incomplete closure of Neural Tube. It is a rare skull defect, with the incidence of 0.8 to 5 per 10,000 live births.

Assessment of early age healthy Georgian children's physical, motor and psychosocial development by BINS (Bayley Infant Neurodevelopmental Screener).

Physical, motor and psychosocial development has been studied in healthy Georgian infants and early age children who were born without biological risks. Neurological, receptive, expressive and cognitive functions were assessed by BINS (Bayley's Infant's Neurodevelopmental screener). Comparing to the norm given by BINS, analyses of variances shows a significant difference of median sum indicators in all age groups.