Publications by authors named "T Ghadban"

Article Synopsis
  • Researchers developed a novel risk score using molecular markers to predict survival in colorectal cancer patients, moving beyond traditional histopathological methods.
  • The study analyzed 1791 patients using immunohistochemistry to measure the levels of H2BUB1, RBM3, and Ki-67, creating a scoring system based on these markers.
  • Results indicated that the new risk score could independently predict patient survival, potentially offering a more personalized approach to treatment than classical methods.
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Background: Insufficient remnant liver volume (RLV) after the resection of hepatic malignancy could lead to liver failure and mortality. Portal vein ligation (PVL) prior to hepatectomy is subsequently introduced to increase the remnant liver volume and improve the outcome of hepatic malignancy. IL-22 has previously been reported to promote liver regeneration, while facilitating tumor development in the liver via Steap4 upregulation.

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Background: Posthepatectomy liver failure (PHLF) remains a life-threatening complication after hepatectomy. To reduce PHLF, a preoperative assessment of liver function is indispensable. For this purpose, Tc-mebrofenin hepatobiliary scintigraphy with SPECT (MSPECT) can be used.

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We present the case of a patient who underwent an open radical prostatectomy with pelvic lymph node dissection (Gleason 4+3, pT3a pN1 R0) in March 2017. In November 2020, prostate-specific membrane antigen (PSMA)-radioguided salvage lymph node dissection was planned due to a single left para-rectal lymph node at a [Ga] Ga-PSMA-I&T PET. In January 2022, the [Ga] Ga-PSMA-I&T PET showed an isolated liver lesion.

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Background: Splenic surgery in hematological disorders requires a well-weighted decision on the indications because the medical treatment has rapidly changed in recent years due to new pharmaceutical approaches.

Objective: Summary of the indications, surgical procedures and perioperative management regarding operative interventions on the spleen in hematological disorders.

Material And Methods: Selective literature search and summary of reviews and guideline recommendations.

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