[Changes of redox processes in liver under pv-88 at experimental hemorrhagic shock].

PV-88 is the Ca2+ L channel blocker from pyrrole compounds, that has been used at hemorrhagic shock - HS (model of Shock was created by the method of (Wiggers-Feine) on 60th minute (intravenous administration, 3 mg/kg). Mean arterial pressure was 40 mmHg. Effects were studied on 80th minute after blood letting.

[Side effects of the combined antiviral therapy in patients with chronic hepatitis C].

The aim of the study is to reveal and treat the side effects of the combined antiviral therapy - Peginterferon and Ribavirin in patients with chronic Hepatitis C. During 2004-2006 years, 40 patients in the ambulatory department of the Infectious Diseases Clinic of the State Medical University were investigated. All the patients were administered pegilated interferon and ribavirin after special procedures.

Hemopoetic organs damage syndrome in patients with chronic viral hepatitis.

Liver cirrhosis and hepatocellular carcinoma are the most frequent and severe complications of chronic hepatitis C. Results of recent investigations indicate that HCV persists and replicates not only in hepatic tissue, but in the other organs as well. The goal of our investigation was to determine hematological disorders during chronic HCV and HCV+HBV hepatitis, to find correlation between activity of chronic hepatitis, stage of cirrhosis, and degree of hematological disorders.

[Highly sensitive methods for the serological,diagnosis of hepatitis B and their clinico-epidemiological significance].

A study was made of HB-virus infection markers in 438 patients of different age with hepatitis B. Highly sensitive methods based on the test systems manufactured in this country and abroad were employed. The authors established the diagnostic importance of HBV markers, studied the prevalence of those markers in parents of the diseased children of the first year of life, demonstrated the clinico-epidemiological importance of highly sensitive methods of serological diagnosis.